Welcome to the Barria Lab!

We are part of the Department of Neurobiology and Biophysics!

We are dedicated to exploring the intricate mechanisms underlying memory formation through our research on the regulation of synaptic transmission and neuronal properties at the cellular and molecular levels. At the core of our work lies a deep fascination with understanding how synapses—the crucial connections between neurons—function and adapt to create a dynamic brain capable of solving complex problems, including understanding its own processes.

Our research spans a broad spectrum, from dissecting the roles of specific molecules and signaling pathways in synaptic plasticity to exploring the dynamic interplay between neurons in neuronal networks. We employ a variety of cutting-edge techniques, including molecular and cellular biology, biochemistry, fluorescence imaging, and electrophysiology, to unravel the complexities of synaptic regulation and the neuromodulation of neuronal intrinsic properties. Through these methods, we aim to shed light on the mechanisms underlying learning and memory, with the broader goal of understanding neurological disorders and advancing their treatment.

Our investigations focus on the hippocampus of rodents and non-human primates as model systems. By studying these organisms, we gain invaluable insights into how different neuromodulators and signaling pathways regulate key synaptic components and neuronal intrinsic properties that are essential for memory formation and proper brain function.

Join us on our journey as we unravel the mysteries of the brain, one synaptic connection at a time.