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PROFESSOR Department Chair
RESEARCH Our lab is interested in neural circuit assembly in development, circuit disassembly in degeneration and circuit reassembly upon cellular regeneration. Our current studies are based on the vertebrate retina of mice, human and non-human primates. We apply a diversity of approach including in vivo and in vitro confocal and multiphoton imaging, serial block-face scanning electron microscopy, transgenic methods and electrophysiology to investigate neuronal structure, function and connectivity in normal and perturbed retinas.
RECENT PUBLICATIONS Circuit Reorganization Shapes the Developing Human Foveal Midget Connectome toward Single-Cone Resolution. LRRTM4: A Novel Regulator of Presynaptic Inhibition and Ribbon Synapse Arrangements of Retinal Bipolar Cells. Distinct Developmental Mechanisms Act Independently to Shape Biased Synaptic Divergence from an Inhibitory Neuron. Dynamic assembly of ribbon synapses and circuit maintenance in a vertebrate sensory system. Synaptic Convergence Patterns onto Retinal Ganglion Cells Are Preserved despite Topographic Variation in Pre- and Postsynaptic Territories. |
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CONTACT Email : wongr2@uw.edu
LAB MEMBERS Wan-Qing Yu
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PUBLICATIONS Google Scholar > |
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