Virginia Merrill Bloedel Hearing Research Center

April 26, 2019

Jennifer Stone, PhD

Jennifer Stone, PhD

Research Professor
Otolaryngology – Head and Neck

Additional Titles: Director of Research
Otolaryngology-Head and Neck Surgery

NIDCD Training Grant for resident research training in Otolaryngology

Research Areas: Balance, hearing
Research Interests: Hearing and balance, development and regeneration of sensory hair cells, biology of hair cell progenitors
Transgenic mouse models, aminoglycoside and genetically mediated hair cell lesions, cell and organ culture, electroporation, immunofluorescence, RNA localization and quantification, confocal and electron microscopy, vestibular behavioral testing
Work Summary: The long-term goal of the Stone lab is to define biological treatments for hearing and balance disorders in humans. Our target for therapy is the hair cell, whose demise underlies many forms of hearing and balance disorders. We are trying to devise strategies to promote regeneration of hair cells, so our studies focus on supporting cells, which are the progenitor cells that form new hair cells. Our efforts are aimed at characterizing properties of hair cell progenitors and identifying signals that control their cell cycle re-entry and transdifferentiation into hair cells following damage.
Links: Lab Website