Matthew Walker, PhD

Research Assistant Professor, Anesthesiology & Pain Medicine

Mitochondria and Metabolism Center 

A Headshot of Rong Tian

Contact

Email: mawalk1@uw.edu

Phone: 206-221-0348

Fax: 206-616-4819

About

To be updated soon

Research

To be updated soon

Honors & Awards
2022
NIH National Research Service Award
Selected Publications

Walker MA, Tian R. NAD(H) in mitochondrial energy transduction: implications
for health and disease. Curr Opin Physiol. 2018 Jun;3:101-109. doi:
10.1016/j.cophys.2018.03.011. Epub 2018 Apr 11. PMID: 32258851; PMCID:
PMC7112453.

Caudal A, Tang X, Chavez JD, Keller A, Mohr JP, Bakhtina AA, Villet O, Chen
H, Zhou B, Walker MA, Tian R, Bruce JE. Mitochondrial interactome quantitation
reveals structural changes in metabolic machinery in the failing murine heart.
Nat Cardiovasc Res. 2022 Sep;1(9):855-866. doi: 10.1038/s44161-022-00127-4. Epub
2022 Sep 9. PMID: 36405497; PMCID: PMC9667921.

Walker MA, Chavez J, Villet O, Tang X, Keller A, Bruce JE, Tian R.
Acetylation of muscle creatine kinase negatively impacts high-energy
phosphotransfer in heart failure. JCI Insight. 2021 Feb 8;6(3):e144301. doi:
10.1172/jci.insight.144301. PMID: 33554956; PMCID: PMC7934860.

Walker MA, Tian R. Raising NAD in Heart Failure: Time to Translate?
Circulation. 2018 May 22;137(21):2274-2277. doi:
10.1161/CIRCULATIONAHA.117.032626. PMID: 29784680; PMCID: PMC5967641.

Walker MA, Chen H, Yadav A, Ritterhoff J, Villet O, McMillen T, Wang Y,
Purcell H, Djukovic D, Raftery D, Isoherranen N, Tian R. Raising NAD<sup>+</sup>
Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart
Failure Independent of Mitochondrial Protein Deacetylation. Circulation. 2023
Dec 19;148(25):2038-2057. doi: 10.1161/CIRCULATIONAHA.123.066039. Epub 2023 Nov
15. PMID: 37965787; PMCID: PMC10842390.