Research Interests

Gene Therapy

Publications

Gottimukkala, K.S.V., Lane, D.D., Cunningham, R.A., Jwa, Y., Adair, J.E. Development of gold nanoparticles for in vivo CRISPR delivery: improving nuclease loading and stability with pre- formed RNP complexes – Oral Presentation at American Society of Gene and Cell Therapy – May 2023 – Los Angeles.

Shahbazi, R., Lane, D.D., Lipson, P., Gottimmukkala, K.S.V., Cunningham, R., Adair, J.E. Hematopoietic stem and progenitor cell specific antibodies and intraosseous administration enhance delivery of a CRISPR nanoformulation – American Society of Gene and Cell Therapy – May 2023 – Los Angeles.

Cassidy, M.E.*, Gottimukkala, K.S.V.*, Lane, D.D., Jwa, Y., Adair, J.E. Human 𝛃-2-microglobulin (B2M) knockdown as an in vitro model to evaluate CRISPR delivery. [In preparation, abstract presentation at 2023 annual meeting of the American Society of Gene and Cell Therapy. *Co- first authors, May 2023 – American Society of Gene and Cell Therapy – May 2023 – Los Angeles.

Shahbazi, R., Lipson, P., Gottimukkala, K.S.V., Lane, D.D., Adair, J.E. (2023). CRISPR Gene Editing of Hematopoietic Stem and Progenitor Cells. In: Pelus, L.M., Hoggatt, J. (eds) Hematopoietic Stem Cells. Methods in Molecular Biology, vol 2567. Humana, New York, NY.

Karthikeya Gottimukkala and Adair Lab members at ASGCT 26th Annual meeting in Los Angeles – May 2023.