Publications

Inheritance of repressed chromatin domains during S phase requires the histone chaperone NPM1 (2022) PMID: #35476441
Escobar TM, Yu JR, Liu S, Lucero K, Vasilyev N, Nudler E, Reinberg D. Sci Adv 22 Apr; 8(17):eabm3945.

Parental nucleosome segregation and the inheritance of cellular identity (2021) PMID: #33500558
TM Escobar, A Loyola, D Reinberg
Nature Reviews Genetics 22 (6), 379-39232021

Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells (2021) PMID: #34075120
A Singh, M Dashynam, B Chim, TM Escobar, X Liu, X Hu, S Patnaik, X Xu, …
Scientific Reports 11 (1), 1-142021

Anxiolytic drug FGIN-1-27 ameliorates autoimmunity by metabolic reprogramming of pathogenic Th17 cells (2020) PMID: #32111885
A Singh, M Dashnyam, B Chim, TM Escobar, AE Dulcey, X Hu, KM Wilson, …
Scientific Reports 10 (1), 1-1422020

Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation during DNA Replication (2019) PMID: #31675501
TM Escobar, O Oksuz, R Saldaña-Meyer, N Descostes, R Bonasio, …
Cell 179 (4), 953-963.e11422019

RNA interactions are essential for CTCF-mediated genome organization (2019) PMID: #31522988
R Saldaña-Meyer, J Rodriguez-Hernaez, T Escobar, M Nishana, …
Molecular Cell 76 (3), 412-422. e5762019

miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate (2019) PMID: #31089138
Y Ji, J Fioravanti, W Zhu, H Wang, T Wu, J Hu, NE Lacey, S Gautam, …
Nature Communications 10 (1), 1-12312019

Transcriptome profiling of human FoxP3+ regulatory T cells (2016) PMID: #26686412
R Bhairavabhotla, YC Kim, DD Glass, TM Escobar, MC Patel, R Zahr, …
Human Immunology 77 (2), 201-213502016

Analysis of the histone H3. 1 interactome: a suitable chaperone for the right event (2015) PMID: #26527279
EI Campos, AH Smits, YH Kang, S Landry, TM Escobar, S Nayak, …
Molecular Cell 60 (4), 697-709532015

Mapping a Th17 network: microRNA and Polycomb in cell fate specification (2014)
T Escobar
Dissertation, Johns Hopkins University, 2014

miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression (2014) PMID: #24856900
TM Escobar, C Kanellopoulou, DG Kugler, G Kilaru, CK Nguyen, …
Immunity 40 (6), 865-8791492014

Expression and regulation of intergenic long noncoding RNAs during T cell development and
differentiation (2013) PMID: #24056746
 G Hu, Q Tang, S Sharma, F Yu, TM Escobar, SA Muljo, J Zhu, K Zhao
Nature Immunology 14 (11), 1190-11983442013

MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer (2013) PMID: #23601686
JC Dudda, B Salaun, Y Ji, DC Palmer, GC Monnot, E Merck, …
Immunity 38 (4), 742-7532632013

STAT3 activates miR-155 in Th17 cells and acts in concert to promote experimental autoimmune uveitis (2013) PMID: #23674757
T Escobar, CR Yu, SA Muljo, CE Egwuagu
Investigative Ophthalmology & Visual Science 54 (6), 4017-4025692013

ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells (2012) PMID: #22666460
XF Liu, TK Bera, C Kahue, T Escobar, Z Fei, GA Raciti, I Pastan
PLoS One 7 (5), e38130302012

DNA methylation status predicts cell type‐specific enhancer activityZ (2011)
M Wiench, S John, S Baek, TA Johnson, MH Sung, T Escobar, …
The EMBO Journal 30 (15), 3028-30392102011

Extranucleosomal DNA binding directs nucleosome sliding by Chd1 (2011) PMID: #21969605
JN McKnight, KR Jenkins, IM Nodelman, T Escobar, GD Bowman
Molecular and Cellular Biology 31 (23), 4746-47591042011