Mikuláš Vlk graduated from Charles University with BSc and MSc degrees in analytical chemistry, working on derivatization of hardly ionizable rhenium complexes and characterization of the products by tandem mass spectrometry and DFT. His PhD project at Charles University and Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences focuses on the study of non-covalent protein complexes and peptide aggregation using native mass spectrometry, cyclic ion mobility, and other structural characterization methods. Mikuláš joined Tureček lab as a graduate student intern from January through September 2024, where his focus is on characterization of nitrile imine photo-cross-linked peptides with UVPD and CID MS/MS and DFT.

Publications:

Zima, V., Vlk, M., Wan, J., Cvačka, J., & Tureček, F. (2023). Tracking Isomerizations of High-Energy Adenine Cation Radicals by UV–Vis Action Spectroscopy and Cyclic Ion Mobility Mass Spectrometry. The Journal of Physical Chemistry A, 127(28), 5899-5913.

Štícha, M., Jelínek, I., & Vlk, M. (2021). Chemical Conversion of Hardly Ionizable Rhenium Aryl Chlorocomplexes with p-Substituted Anilines. Molecules, 26(11), 3427.

Conferences:

1. Poster presentation: „Utilization of Cyclic Ion Mobility Spectrometry for Detection and Characterization of Aβ(1-42) Oligomers“, International Conference on Alzheimer’s and Parkinson’s Disease and related neurological disorders (AD/PD), Göthenburg, Sweden 2023

2. Poster presentation: „Utilization of Ion Mobility – Mass Spectrometry for Detection and Characterization Aβ(1-42) Oligomers“ Symposium on Structural Proteomics , Utrecht, Netherlands 2023

3. Poster presentation: : „Advancing biomolecular analysis by cyclic ion mobility-mass spectrometry

19th International Student Conference ‘Modern Analytical Chemistry“, Prague, Czech Republic 2023