Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetič A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale M Jr, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D. Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice. Sci Transl Med. 2022 May 25;14(646):eabn1252. doi: 10.1126/scitranslmed.abn1252. Epub 2022 May 25. PubMed PMID: 35412328; PubMed Central PMCID: PMC9258422.
Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Barnes CO, Hsiang TY, Esser-Nobis K, Yu K, Reneer ZB, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric RS, Fuller DH, Walkey CD, Ross TM, Swanson R, Bjorkman PJ, Gale M Jr, Blancas-Mejia LM, Yen HL, Silva DA. De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.Science. 2020 Dec 4;370(6521):1208-1214. doi: 10.1126/science.abe0075. Epub 2020 Nov 5. PubMed PMID: 33154107; PubMed Central PMCID: PMC7920261.
Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O’Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, Zepeda SK, Starr T, Hsieh CL, Fiala B, Wrenn S, Pettie D, Sydeman C, Johnson M, Blackstone A, Ravichandran R, Ogohara C, Carter L, Tilles SW, Rappuoli R, O’Hagan DT, Van Der Most R, Van Voorhis WC, McLellan JS, Kleanthous H, Sheahan TP, Fuller DH, Villinger F, Bloom J, Pulendran B, Baric R, King N, Veesler D. Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines. bioRxiv. 2021 Mar 16;. doi: 10.1101/2021.03.15.435528. PubMed PMID: 33758839; PubMed Central PMCID: PMC7986998.
Erasmus, JH, Fuller DH(2020). Preparing for pandemics: RNA vaccines at the forefront. Mol Ther. Jul 8;28(7):1559-1560. doi: 10.1016/j.ymthe.2020.06.017. PMID: 32579882.
Fuller DH, Berglund P. Amplifying RNA Vaccine Development. N Engl J Med. 2020 Jun 18;382(25):2469-2471. doi: 10.1056/NEJMcibr2009737. PubMed PMID: 32558474., Berglund P. Amplifying RNA Vaccine Development. N Engl J Med. 2020 Jun 18;382(25):2469-2471. doi: 10.1056/NEJMcibr2009737. PubMed PMID: 32558474.
Gorini G, Fourati S, Vaccari M, Rahman MA, Gordon SN, Brown DR, Law L, Chang J, Green R, Barrenäs F, Liyanage NPM, Doster MN, Schifanella L, Bissa M, Silva de Castro I, Washington-Parks R, Galli V, Fuller DH, Santra S, Agy M, Pal R, Palermo RE, Tomaras GD, Shen X, LaBranche CC, Montefiori DC, Venzon DJ, Trinh HV, Rao M, Gale M Jr, Sekaly RP, Franchini G. Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition. PLoS Pathog. 2020 Mar;16(3):e1008377. doi: 10.1371/journal.ppat.1008377. eCollection 2020 Mar. PubMed PMID: 32163525; PubMed Central PMCID: PMC7093029.
Wood MP, Wood L, Templeton M, Fisher B, Lippy A, Joes CI, Arlehamn L, Fuller J, Murapa P, Jaspan H, Fuller DH, Sodora D (2020). Transient immune activiation associated with BCG vaccination of infant rhesus macaques is not sufficient to influence oral simian immunodeficiency virus infection. JIDorg/10.1093/infdis/jiz382; PMID: 31605528.
Hessell AJ, Powell R, Jiang X, Luo C, Weiss S, Dussupt V, Itri V, Fox A, Shapiro MB, Pandey S, Cheever T, Fuller DH, Park B, Krebs SJ, Totrov M, Haigwood NL (2019). Multimeric epitope-scaffold HIV vaccine target V1V2 and differentially tune polyfunctional antibody responses. Cell Reports 28 (4): 877-895 PMID 31340151
O’Connor MA, Munson PV, Tunggal HC, Hajari N, Lewis TB, Bratt D, Moats C, Smedley J, Bagley KC, Mullins JI, Fuller DH (2019). Mucosal T helper 17 and T regulatory cell homeostasis correlates with acute SIV viremia and responsiveness to antiretroviral therapy in macaques. AIDS Research and Human Retroviruses; org/10.1089/aid.2018.0184, PMID: 30398361
Munson PV, Tunggal H, O’Connor M, Bratt D, May A, Wangari S, Agricola B, Smedley J, Fuller JT, Kulkarni V, Felber, BK, Pavlakis GN, Mullins JI, Fuller DH (2018). Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during chronic viral infection. Human Vaccines and Immunotherapy DOI: 1080/21645515.2018.1448328; PMID: 29648490
Koday MT, Leonard J, Fuller JT, Bratt D, Koday M, Fuller DH (2017). Multivalent Influenza DNA Vaccine Induces Potent Antibodies and Broadly-Specific T Cell Responses in Non-human Primates, PLoS Onehttps://doi.org/10.1371/journal.pone.0189780. PMID: 29267331
Chevalier A, Silva D-A, Rocklin G-J, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam K-H,Yao G, Bahl CD, Miyashita S-I, Inna G, Fuller JT, Koday MT, Jenkins C, Colvin T, Carter L, Bohn A, Bryan CM, Fernandez-Velasco DA, Stewart L, Dong M, Huang X, Jin R, Wilson IA, Fuller DH, Baker D (2017). Massively parallel de novo protein design for targeted therapeutics, Nature 550 (7674): 74-79; DOI: doi:10.1038/nature23912, PMID: 28953867.
Strauch EM, Bernard SM, Bohn AJ, Lee PS, Anderson, CE, Nieusma T, Holstein CA, La D, Garcia NK, Hooper KA, Ravichandran R, Nelson J, Sheffler W, Bloom JD, Lee KK, Ward AB, Yager P, Fuller DH, Wilson IA, Baker D (2017). Design of trimeric influenza neutralizing proteins targeting the hemagglutinin receptor binding site. Nature Biotechnology 35(7): 667-71. DOI:1038/nbt.3907. PMID: 28604661.
Dross SE, Munson P, Kim, SE, Bratt, D, Gervassi, A, Fuller DH, Horton, H (2016). Kinetics of myeloid derived suppressor cell frequency and function during SIV infection and combination antiretroviral therapy. J Immunol. 198(2): 757-766; DOI: 4049/jimmunol.1600759; PMID: 27974456.
McBurney SP, Sunshing JE, Huynh GS, Sutton WF, Fuller DH, Haigwood NL, Messer WB (2016). Evaluation of protection induced by a dengue virus serotype 2 envelope domain III protein scaffold/DNA vaccine in non-human primates. Vaccine 24;34(30):3500-7. doi: 10.1016/j.vaccine.2016.03.108. PMID: 27085173.
Stone BC, Kas A, Billman ZP, Fuller DH, Fuller JT, Shendure J, Murphy SC. (2016). Complex minigene library vaccination for discovery of pre-erythrocytic Plasmodium T cell antigens PLoS One 11(4): e0153449. doi:10.1371/journal.pone.0153449, PMID: 27070430, PCMID:PMC 4829254.
Hessell A, Malherbe D, Pissani F, McBurney S, Krebs S, Gomes M, Pandey S, Sutton W, Burwitz B, Gray M, Robins H, Park B, Sacha J, LaBranche C, Fuller DH, Montefiori D, Stamatatos L, Sather N, Haigwood N. (2016). Achieving potent autologous neutralizing antibody responses against Tier 2 viruses by strategic selection of Env immunogen, Journal of Immunology 196(7):3064-78. doi: 10.4049/jimmunol.1500527, PMID: 26944928, PCMID:PMC 4797725.
Rosinski SL, Stone, BC, Graves S, Fuller DH, Fuller JT, Storb R (2016). Donor Conversion Following Minor Antigen Vaccine-Sensitized DLI Does Not Correlate with the Level of Donor Sensitization. Transplantation Direct 8;2(5):e71. doi: 10.1097/TXD.0000000000000583. PMID:27430015.