We are excited about the upcoming Biophysical Society meeting in San Diego, February 15-19. This year we will have a strong showing of our current mechanistic and translational research, with 10 presentations from our lab and with collaborators. Here is a list of the scheduled presentations, with the presenter’s name in bold. If you plan to attend the meeting, please stop by to check them out and give us your feedback.
Sunday, February 16, 2020
Platform: Excitation-Contraction Coupling, 4:00 pm – 6:00 pm, Room 31ABC
169-Plat 5:45 pm
THE E258K-MYPBC3 MODELLED IN HCM PATIENT-DERIVED CARDIOMYOCYTES TO IDENTIFY THE PRIMARY IMPACT OF THE MUTATION VERSUS THE SECONDARY CHANGES DUE TO CARDIAC REMODELING. J. M. Pioner, Sonette Steczina, Giulia Vitale, Saffie Mohran, Chiara Palandri, Lorenzo Santini, Silvia Querceto, Marianna Langione, Elisabetta Cerbai, Chiara Tesi, Raffaele Coppini, Cecilia Ferrantini, Corrado Poggesi, Michael Regnier
Monday, February 17, 2020
Muscle Regulation
1276-Pos Board B344
EXPLORING THE EFFECTS OF 2.DEOXY-ATP ON SERCA 2A USING MULTISCALE MODELING. Kimberly J. McCabe, Sophia P. Hirakis, Abigail E. Teitgen, Alexandre B. Duclos, Michael Regnier, Rommie E. Amaro, Andrew D. McCulloch
Skeletal Muscle Mechanics, Structure, and Regulation
1358-Pos Board B426
DEVELOPMENT OF MECHANICAL AND STRUCTURAL DYSFUNCTION IN SKELETAL MUSCLE FROM A DUCHENE MUSCULAR DYSTROPHY RAT MODEL. Saffie Mohran, Chen-Ching Yuan, Shawn M. Luttrell, Weikang Ma, Thomas C. Irving, David L. Mack, Michael Regnier
1362-Pos Board B430
USE OF CELLS FROM REMOTELY COLLECTED URINE TO GENERATE HUMAN INDUCED PLURIPOTENT STEM CELLS AND MYOFIBERS THAT RECAPITULATE UNCONVENTIONAL MYOPATHIES. Shawn M. Luttrell, Saffie Mohran, Kati Buckingham, Michael J. Bamshad, Michael Regnier, David L. Mack
Tuesday, February 18, 2020
Platform: Cardiac Muscle Regulation, 8:15 am – 10:15 am, Room 30ABC
1600-Plat 9:00 am
TWO SMALL MOLECULE INHIBITORS OF MYOSIN DECREASE FORCE AND INCREASE RATES OF RELAXATION IN DEMEMBRANATED RAT LEFT VENTRICULAR TISSUE. Kristina B. Kooiker, Qing-Fen Gan, Ming Yu, Yuanhua Cheng, Na Sa, Min Zhong, Tim McMillen, Farid Moussavi-Harami, Michael Regnier
Cardiac Muscle Mechanics and Structure
2072-Pos Board B342
CROSS-SPECIES DYNAMICS OF MYOSIN IN PRE-POWERSTROKE STATES. Matthew C. Childers, Valerie Daggett, Michael Regnier
2073-Pos Board B343
EFFECT OF MYOSIN ISOFORM ON MECHANICS IN INTACT CARDIAC TRABECULAE FROM MICE, RATS AND HUMANS. Srboljub M. Mijailovich, Momcilo Prodanovic, Corrado Poggesi, Michael Regnier, Michael A. Geeves
2085-Pos Board B355
NUCLEOTIDE-DEPENDENT ALLOSTERIC COMMUNICATION IN MYOSIN. Matthew C. Childers, Valerie Daggett, Michael Regnier
2091-Pos Board B361
HIPSCS DERIVED CARDIOMYOCYTES OVEREXPRESSING DEOXY ATP TO RESTORE CARDIAC FUNCTION. Ketaki N. Mhatre, Julie Mathieu, Charles E. Murry, Michael Regnier
Wednesday, February 19, 2020
Cardiac Muscle Regulation
2903-Pos Board B449
TWO MYOFILAMENT-BASED APPROACHES TO PREVENT GENETIC DILATED CARDIOMYOPATHY. Claire E. Branley, Farid Moussavi-Harami, Kristina B. Kooiker, Michael Regnier, Jil C. Tardiff, Joelle Tudor, Jeremy Freeman