Work performed in collaboration with Sameer Sheth, Wayne Goodman, and Nicole Provenza at Baylor College of Medicine has established a new biomarker for OCD detailed in a new Nature Medicine publication available here.
Attending the 10th Annual BRAIN Initiative Meeting and presenting a development update with the CorTec Brain Interchange
I’ll be attending the annual BRAIN Initiative Meeting in Washington DC this coming weekend to present our group’s ongoing development progress with the CorTec Brain Interchange to support our upcoming stroke study. The poster is accessible via this link. Also check out the OpenMind Consortium’s poster detailing the impact of our ongoing technological dissemination efforts!
Research progress being presented at 2024 American Society for Stereotactic and Functional Neurosurgery Meeting
My Bioengineering PhD Student Raphael Bechtold and collaborators from Baylor College of Medicine are all heading to Nashville for the 2024 American Society for Stereotactic and Functional Neurosurgery Meeting to present our ongoing work studying the use of neuromodulation therapies for neuropsychiatric disorders! Check out their work –
- Bechtold, N. Provenza, N. Giridharan, A. Allam, S. Rajesh, A. Gandhi, G. Reyes, S. Reddy, E. Storch, S. A. Sheth, W. K. Goodman, and J. Herron, “Offline simulation of adaptive deep brain stimulation algorithm classification for performance characterization during provocation of OCD symptoms”
- Giridharan, N. Provenza, A. Allam, R. Bechtold, N. Diab, S. Rajesh, S. Reddy, G. Reyes, E. Dastin-van Rijn, A. Gandhi, S. Hirani, H. Dang, G. Banks, M. Avendano-Ortega, S. McKay, D. Borton, E. Storch, J. Herron, W. Goodman, S. Sheth “Low-Frequency Power in The Ventral Capsule/Ventral Striatum and Orbitofrontal Cortex: A Neural Biomarker of Obsessive-Compulsive Symptom Severity”
- Provenza, G. Reyes, K, Katlowitz, R. Bechtold, N. Diab, S. Reddy, A. Allam, A. Gandhi, S. Hirani, N. Giridharan, G. Banks, M. Hasen, B. Shofty, B. Hayden, J. Cohn, E. Storch, J. Herron, M. Phillips, W. Goodman, S. Sheth “Deep Brain Stimulation of the Ventral Capsule and Ventral Striatum Drives Approach Behavior and High Beta Power in Ventrolateral Prefrontal Cortex”
- Provenza, S. Reddy, A. Allam, S. Rajesh, N. Diab, R. Caston, K. Katlowitz, A. Gandhi, H. Dang, R. Najera, N. Giridharan, F. Momin, M. Hasen, G. Banks, B. Shofty, B. Hayden, J. Herron, E. Storch, A. Patel, W. Goodman, S. Sheth “DBS Disruption of Neural Rhythms Predicts Shifts in Clinical Response in Obsessive-Compulsive Disorder”
- Kang, W. Mahaphanit, N. Provenza, M. Nassar, A. Allam, R. Bechtold, N. Diab, S. Rajesh, S. Reddy, G. Reyes, E. Dastin-van Rijn, A. Gandhi, S. Hirani, G. Banks, H. Dang, M. Avendano-Ortega, S. McKay, D. Borton, M. Frank, E. Storch, J. Herron, W. Goodman, B. Hayden, S. Sheth “The Effect of Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder in Cognitive Self-Control Under Uncertainty”
FDA approves our Investigational Device Exemption for an Early Feasibility Study to rehabilitate stroke patients using CorTec’s Closed-Loop Brain Interchange implant system
We are excited to announce that the FDA approved our Investigational Device Exemption application to make use of the CorTec Brain Interchange in a study seeking to enhance stroke rehabilitation through the use of neuroplasticity-inducing stimulation! Pending IRB approval, we will be seeking individuals with persistent upper limb disability following stroke to participate in this first-of-it’s-kind study with this new device. More information will be coming soon, and for more information check out CorTec’s press release here.
New article in Nature Reviews Bioengineering – “The Convergence of Neuromodulation and Brain-Computer Interfaces”
I’m happy to announce that Nature Reviews Bioengineering published an article I drafted with the OpenMind Consortium leadership team detailing the ongoing technological converging of the fields of Brain Computer Interfaces and Neuromodulation. I encourage you to check it out here!
“Data processing techniques impact quantification of cortico-cortical evoked potentials” in Journal of Neuroscience Methods details the impact of signal processing on evoked-potential analysiis
GridLab-affiliated Neuroscience PhD student Lila Levinson’s work to investigate the impact of signal processing methods on neurological evoked-potential characterization has been published in the Journal of Neuroscience Methods in “Data processing techniques impact quantification of cortico-cortical evoked potentials“. Great work on this project Lila – this has been a monster of a paper and it was a pleasure working with you on it!
Panel member for the “Cognitive Connections: Exploring Brain-Computer-Interfaces through Systems and Experiments” session at the 2024 IEEE Custom Integrated Circuits Conference
I’m an invited panelist at the upcoming 2024 IEEE Custom Integrated Circuits Conference (CICC) to discuss my work in the fields of Brain Computer Interfaces and Neuromodulation!
The session has an exciting lineup which also includes:
- Shadi Dayeh, University of California, San Diego, USA
- Roman Genov, University of Toronto, Canada
- Minkyu Je, KAIST, South Korea
- Mahsa Shoaran, EPFL, Switzerland
Looking forward to seeing you all there and having a great discussion!
Congratulations to GridLab mentee Dr. Lila Levinson on her successful Neuroscience PhD defense!
Congratulations to GridLab’s Dr. Lila Levinson who just successfully defended her Neuroscience Thesis “Cortico-Cortical Evoked Potentials to Probe Neuroplasticity: Methodological Considerations and Contextualization” – I’m excited to see what you do next Lila!
Research progress being presented at 2023 Society for Neuroscience this November
While I won’t be able to attend SFN 2023 in Washington DC later this year, I am sending several students from the lab to present their latest results. PhD student Hanbin Cho’s poster is detailing the latest results of her phasic-stimulation system with the CorTec Brain Interchange and PhD student Raphael Bechtold’s poster addresses artifacts in adaptive Deep Brain Stimulation applications where patients are implanted with multiple devices. Make sure you swing by and check out their work!
I also want to give a big shout-out to my collaborators who are also presenting results that I’ve been involved in! Please swing by these posters as well:
- N. Giridharan, N. Provenza, S. Rajesh, N. Diab, R. Bechtold, E.M. Dastin-van Rijn, A. Allam, G. Reyes, S. Reddy, M. Avendano-Ortega, S. McKay, G. Banks, D.A. Borton, E. Storch, J. Herron, W.K. Goodman, S.A. Sheth “Low-frequency power in the ventral capsule/ventral striatum and orbitofrontal cortex: a neural biomarker of obsessive-compulsive symptom severity”
- K. Wilkins, E. Lambert, J. Melbourne, M. Petrucci, A. Gala, P. Akella, L. Parisi, S. Aditham, G. Orthlieb, J. Herron, H. Bronte-Stewart, “Beta Burst Driven Closed Loop Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease”
- Akella, R. Crockett, K. Wilkins, J. Herron, H. Bronte-Stewart, “Know your limit, rest within it: investigating the effectiveness of neural adaptive deep brain stimulation for rest tremor.”
- Parisi, P. Akella, E. Lambert, J. Melbourne, A. Gala, C. Cui, Y. Kehnemouyi, J. O’Day, K. Wilkins, M. Petrucci, S. Aditham, G. Orthlieb, J. Herron, H. Bronte-Stewart, “Closed loop deep brain stimulation using real-time kinematic inputs for gait impairment and freezing of gait in Parkinson’s disease”
- M.E. Alarie: Other; Funded by NSF GRFP. N.R. Provenza, J. Herron, W.F. Asaad, “Automated neural-behavioral data alignment for fully implantable DBS platforms”
Start of the Academic Year 2023-2024
This quarter I’ll be teaming up with CSE Professor Rajesh Rao to teach Neural Engineering: BIOEN 460/560, EE 460/560, CSE 490N. The course is focused on introducing the wide field of neural engineering to senior undergraduates and graduate students, including the organization of the nervous system, brain computer interfaces, neural device design, and neuroethics. Thanks in advance to the guest speakers that have also agreed to present to the class, and for anyone who is registered for the course and reading this – looking forward to seeing you in class!