I’ll be attending the annual BRAIN Initiative Meeting in Washington DC this coming weekend to present our group’s ongoing development progress with the CorTec Brain Interchange to support our upcoming stroke study. The poster is accessible via this link. Also check out the OpenMind Consortium’s poster detailing the impact of our ongoing technological dissemination efforts!
Conference News
Research progress being presented at 2024 American Society for Stereotactic and Functional Neurosurgery Meeting
My Bioengineering PhD Student Raphael Bechtold and collaborators from Baylor College of Medicine are all heading to Nashville for the 2024 American Society for Stereotactic and Functional Neurosurgery Meeting to present our ongoing work studying the use of neuromodulation therapies for neuropsychiatric disorders! Check out their work –
- Bechtold, N. Provenza, N. Giridharan, A. Allam, S. Rajesh, A. Gandhi, G. Reyes, S. Reddy, E. Storch, S. A. Sheth, W. K. Goodman, and J. Herron, “Offline simulation of adaptive deep brain stimulation algorithm classification for performance characterization during provocation of OCD symptoms”
- Giridharan, N. Provenza, A. Allam, R. Bechtold, N. Diab, S. Rajesh, S. Reddy, G. Reyes, E. Dastin-van Rijn, A. Gandhi, S. Hirani, H. Dang, G. Banks, M. Avendano-Ortega, S. McKay, D. Borton, E. Storch, J. Herron, W. Goodman, S. Sheth “Low-Frequency Power in The Ventral Capsule/Ventral Striatum and Orbitofrontal Cortex: A Neural Biomarker of Obsessive-Compulsive Symptom Severity”
- Provenza, G. Reyes, K, Katlowitz, R. Bechtold, N. Diab, S. Reddy, A. Allam, A. Gandhi, S. Hirani, N. Giridharan, G. Banks, M. Hasen, B. Shofty, B. Hayden, J. Cohn, E. Storch, J. Herron, M. Phillips, W. Goodman, S. Sheth “Deep Brain Stimulation of the Ventral Capsule and Ventral Striatum Drives Approach Behavior and High Beta Power in Ventrolateral Prefrontal Cortex”
- Provenza, S. Reddy, A. Allam, S. Rajesh, N. Diab, R. Caston, K. Katlowitz, A. Gandhi, H. Dang, R. Najera, N. Giridharan, F. Momin, M. Hasen, G. Banks, B. Shofty, B. Hayden, J. Herron, E. Storch, A. Patel, W. Goodman, S. Sheth “DBS Disruption of Neural Rhythms Predicts Shifts in Clinical Response in Obsessive-Compulsive Disorder”
- Kang, W. Mahaphanit, N. Provenza, M. Nassar, A. Allam, R. Bechtold, N. Diab, S. Rajesh, S. Reddy, G. Reyes, E. Dastin-van Rijn, A. Gandhi, S. Hirani, G. Banks, H. Dang, M. Avendano-Ortega, S. McKay, D. Borton, M. Frank, E. Storch, J. Herron, W. Goodman, B. Hayden, S. Sheth “The Effect of Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder in Cognitive Self-Control Under Uncertainty”
Panel member for the “Cognitive Connections: Exploring Brain-Computer-Interfaces through Systems and Experiments” session at the 2024 IEEE Custom Integrated Circuits Conference
I’m an invited panelist at the upcoming 2024 IEEE Custom Integrated Circuits Conference (CICC) to discuss my work in the fields of Brain Computer Interfaces and Neuromodulation!
The session has an exciting lineup which also includes:
- Shadi Dayeh, University of California, San Diego, USA
- Roman Genov, University of Toronto, Canada
- Minkyu Je, KAIST, South Korea
- Mahsa Shoaran, EPFL, Switzerland
Looking forward to seeing you all there and having a great discussion!
Research progress being presented at 2023 Society for Neuroscience this November
While I won’t be able to attend SFN 2023 in Washington DC later this year, I am sending several students from the lab to present their latest results. PhD student Hanbin Cho’s poster is detailing the latest results of her phasic-stimulation system with the CorTec Brain Interchange and PhD student Raphael Bechtold’s poster addresses artifacts in adaptive Deep Brain Stimulation applications where patients are implanted with multiple devices. Make sure you swing by and check out their work!
I also want to give a big shout-out to my collaborators who are also presenting results that I’ve been involved in! Please swing by these posters as well:
- N. Giridharan, N. Provenza, S. Rajesh, N. Diab, R. Bechtold, E.M. Dastin-van Rijn, A. Allam, G. Reyes, S. Reddy, M. Avendano-Ortega, S. McKay, G. Banks, D.A. Borton, E. Storch, J. Herron, W.K. Goodman, S.A. Sheth “Low-frequency power in the ventral capsule/ventral striatum and orbitofrontal cortex: a neural biomarker of obsessive-compulsive symptom severity”
- K. Wilkins, E. Lambert, J. Melbourne, M. Petrucci, A. Gala, P. Akella, L. Parisi, S. Aditham, G. Orthlieb, J. Herron, H. Bronte-Stewart, “Beta Burst Driven Closed Loop Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease”
- Akella, R. Crockett, K. Wilkins, J. Herron, H. Bronte-Stewart, “Know your limit, rest within it: investigating the effectiveness of neural adaptive deep brain stimulation for rest tremor.”
- Parisi, P. Akella, E. Lambert, J. Melbourne, A. Gala, C. Cui, Y. Kehnemouyi, J. O’Day, K. Wilkins, M. Petrucci, S. Aditham, G. Orthlieb, J. Herron, H. Bronte-Stewart, “Closed loop deep brain stimulation using real-time kinematic inputs for gait impairment and freezing of gait in Parkinson’s disease”
- M.E. Alarie: Other; Funded by NSF GRFP. N.R. Provenza, J. Herron, W.F. Asaad, “Automated neural-behavioral data alignment for fully implantable DBS platforms”
Mentored student work at the UW Undergraduate Research Symposium
GridLab-affiliated undergraduate students Iman Tanumihardja and Medha Gupta presented their work with recent PhD graduate Courtnie Paschall and post-bacc/research analyst Sophia Lowe-Hines on using virtual reality to induce the rubber hand illusion at the University of Washington’s annual undergraduate research symposium! Great work team!
2023 IEEE EMBS Conference on Neural Engineering (NER)
Two of my PhD students and I travelled to Baltimore this week to present our latest work at the IEEE NER Conference. It was a great conference with fascinating talks and a wonderful opportunity to get back together with the field in-person again.
CSE PhD Student Ellie Strandquist presented her Weill-Neurohub funded work developing tools to collect extensive video and patient data from study participant’s homes who are enrolled in an adaptive deep brain stimulation study. This work was performed in collaboration with Simon Little of UCSF, Jack Gallant at UC Berkeley, as well as students and research staff distributed amongst the three Universities. Her work can be read in more detail here: https://ieeexplore.ieee.org/abstract/document/10123851
ECE PhD student Hanbin Cho presented her work developing software interfaces for use with the CorTec Brain Interchange and demonstrated the use of closed-loop stimulation with the platform. Her work can be read in more detail here: https://ieeexplore.ieee.org/abstract/document/10123808
Upcoming research papers to be presented at the IEEE EMBS Conference on Neural Engineering in Baltimore this April
I and several of my students will be attending the upcoming IEEE EMBCS Conference on Neural Engineering in Baltimore in a little over a month! We have two papers accepted, come check out our posters at the Thursday poster sessions!
Second year ECE PhD student Hanbin Cho will be presenting her ongoing work developing a gRPC-enabled microservice to enable flexible use of the CorTec Brain Interchange in upcoming clinical studies. Her paper, ID# 1570869464, is titled “Open Mind Neuromodulation Interface for the CorTec Brain Interchange (OMNI-BIC): an investigational distributed research platform for next-generation clinical neuromodulation research” and there is a preprint available here.
Third year CSE PhD student Gabrielle Strandquist will be presenting her ongoing work developing methods for video-based bradykinesia symptom assessment from remote monitoring platforms. Her paper, ID# 1570869723, is titled “In-Home Video and IMU Kinematics of Self Guided Tasks Correlate with Clinical Bradykinesia Scores” and there is a preprint available here.
2022 Society for Neuroscience
Congratulations to all the students and collaborators who have had their work accepted for presentations at the 2022 Annual Meeting for the Society of Neuroscience!
| 059.04 – Kinematic Closed Loop Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease G. C. L. ORTHLIEB1, Y. KEHNEMOUYI1, H. DORRIS1, J. O’DAY1, K. B. WILKINS1, S. ADITHAM1, M. N. PETRUCCI1, E. LAMBERT1, J. MELBOURNE1, C. DIEP1, S. HOFFMAN1, J. PARKER1, J. A. HERRON2, *H. BRONTE-STEWART1; 1Stanford Univ., Palo Alto, CA; 2Univ. of Washington, Univ. of Washington, Seattle, WA |
| Nov. 12, 2022, 1:00 PM – 5:00 PM 059.05 – Calibration of closed loop deep brain stimulation in Parkinson’s disease J. A. MELBOURNE1, *K. B. WILKINS1, E. F. LAMBERT1, M. N. PETRUCCI1, Y. M. KEHNEMOUYI1, G. C. L. ORTHLIEB1, H. DORRIS1, C. DIEP1, S. ADITHAM1, J. A. HERRON2, H. M. BRONTE-STEWART1; 1Stanford Univ., Stanford Univ., Palo Alto, CA; 2Univ. of Washington, Univ. of Washington, Seattle, WA |
| Nov. 12, 2022, 1:00 PM – 5:00 PM 059.06 – Closed Loop Deep Brain Stimulation Using Beta Bursts for Freezing of Gait in Parkinson’s Disease *S. ADITHAM1, M. N. PETRUCCI1, K. B. WILKINS1, E. LAMBERT1, J. MELBOURNE1, S. L. HOFFMAN1, Y. M. KEHNEMOUYI1, G. C. L. ORTHLIEB1, J. E. PARKER1, H. DORRIS1, C. DIEP1, R. W. ANDERSON1, J. A. HERRON2, H. M. BRONTE-STEWART1; 1Stanford Univ., Stanford, CA; 2Univ. of Washington, Univ. of Washington, Seattle, WA |
| Nov. 14, 2022, 1:00 PM – 5:00 PM 389.01 – Rapid offline identification of neural triggers for a virtual reality brain computer interface (VR-BCI) with intracranial electrodes in humans *C. PASCHALL1, E. TANUMIHARDJA2, K. E. WEAVER3, B. L. GRANNAN4, A. KO5, J. S. HAUPTMAN4, J. G. OJEMANN4, R. P. RAO2, J. A. HERRON4; 1Bioengineering Dept., 2Paul G. Allen Sch. for Computer Sci. and Engin., 3Radiology, 4Dept. of Neurolog. Surgery, 5Univ. of Washington, Seattle, WA |
| Nov. 14, 2022, 1:00 PM – 5:00 PM 401.12 – The rubber hand illusion in virtual reality *S. LOWE-HINES1, E. TANUMIHARDJA2, C. PASCHALL3, B. L. GRANNAN1, A. KO1, J. S. HAUPTMAN1, J. G. OJEMANN1, R. P. RAO2, J. A. HERRON1; 1Dept. of Neurolog. Surgery, 2Paul G. Allen Sch. for Computer Sci. and Engin., 3Dept. of Bioengineering, Univ. of Washington, Seattle, WA |
| Nov. 14, 2022, 1:00 PM – 5:00 PM 414.01 – Artifact characterization and mitigation techniques during concurrent sensing and stimulation using bidirectional deep brain stimulation platforms *M. E. ALARIE1, N. R. PROVENZA2, M. AVENDANO-ORTEGA3, S. MCKAY3, A. S. WAITE1, R. K. MATHURA2, J. A. HERRON4, S. A. SHETH2, D. A. BORTON1, W. K. GOODMAN3; 1Engin., Brown Univ., Providence, RI; 2Neurosurg., 3Menninger Dept. of Psychiatry and Behavioral Sci., Baylor Col. of Med., Houston, TX; 4Neurolog. Surgery, Univ. of Washington, Seattle, WA |
| Nov. 14, 2022, 1:00 PM – 5:00 PM 414.07 – Stability and sensitivity of cortical evoked potential measures in human stereoencephalography *L. H. LEVINSON1, S. SUN2, C. J. PASCHALL2, K. E. WEAVER3, J. A. HERRON4, A. L. KO4, S. I. PERLMUTTER5, J. G. OJEMANN4; 1Neurosci., 2Bioengineering, 3Radiology, 4Neurolog. Surgery, 5Dept Physiol. & Biophysics, Washington Natl. Primate Res. Ctr., Univ. of Washington, Seattle, WA |
| Nov. 14, 2022, 1:00 PM – 5:00 PM 414.09 – Comparison of human local field potential dynamics during different electrical stimulation conditions *S. H. SUN1, L. LEVINSON2, C. J. PASCHALL1, K. E. WEAVER3, J. S. HAUPTMAN6, A. KO4, J. A. HERRON4, J. G. OJEMANN4, R. P. RAO5; 1Bioengineering, 2Neurosci., 3Radiology, 4Neurolog. Surgery, 5Paul G. Allen Sch. for Computer Sci. and Engin., Univ. of Washington, Seattle, WA; 6Neurosurg., Seattle Children’s Hosp., Seattle, WA |
| Nov. 15, 2022, 10:30 AM – 10:45 AM 432.11 – Identification of candidate neural biomarkers of obsessive-compulsive symptom intensity and response to deep brain stimulation *N. R. PROVENZA1, C. PRAKASH SWAMY2, L. BRANCO2, E. DASTIN-VAN RIJN3, S. HINDUJA4, M. ALARIE5, A. S. WAITE5, M. AVENDANO-ORTEGA1, S. MCKAY1, G. S. VOGT6, H. DANG1, R. MATHURA1, B. ROARR5, A. D. WIESE1, J. XU1, A. VISWANATHAN1, B. SHOFTY1, J. A. HERRON7, M. T. HARRISON5, K. R. BIJANKI1, E. A. STORCH1, J. F. COHN4, D. A. BORTON5, N. F. INCE2, W. K. GOODMAN1, S. A. SHETH1; 1Baylor Col. of Med., Houston, TX; 2Univ. of Houston, Houston, TX; 3Biomed. Engin., Univ. of Minnesota, Twin Cities, Minneapolis, MN; 4Univ. of Pittsburgh, Pittsburgh, PA; 5Brown Univ., Providence, RI; 6Psychological and Brain Sci., Texas A&M Univ., College Station, TX; 7Dept. of Neurolog. Surgery, Univ. of Washington, Seattle, WA |
| Nov. 16, 2022, 1:00 PM – 5:00 PM 710.09 – Decoding subjective pain experience from multi-day intracranial electroencephalography in humans *T. V. PHAM1, S. H. SUN1, K. E. WEAVER2, J. A. HERRON3,4, A. L. KO3, J. G. OJEMANN3, R. P. N. RAO5,6,4; 1Bioengineering, 2Radiology, 3Neurolog. Surgery, 4Electrical and Computer Engin., 5Paul G. Allen Sch. for Computer Sci. and Engin., Univ. of Washington, Seattle, WA; 6Ctr. for Neurotechnology, Seattle, WA |
Presenting at the IEEE Brain Discovery Neurotechnology Workshop
I will be a presenting ongoing developments in the field of adaptive Deep Brain Stimulation at the IEEE Brain Discovery Neurotechnology Workshop – Brain, Mind, and Body Symposium (BMB 2022) this November. The workshop is a satellite event for the 2022 Society for Neuroscience (SFN) conference that will be held in San Diego.
Registration to the workshop is free, so come by and see my talk at 9AM on Thursday November 10th. Thank you very much to the organizers of the event for inviting me to give this plenary talk! The rest of the agenda is available here.
Congratulations to PhD student Samantha Sun for being awarded the IEEE Brain Best Paper at the 2022 Systems, Man, and Cybernetics Conference!
Congratulations to Samantha Sun who presented her work titled “Human Intracortical Responses to Varying Electrical Stimulation Conditions Are Separable in Low-Dimensional Subspaces,” for which she was awarded the IEEE Brain Best Student Paper and was one of only four finalists for the overall IEEE SMC Best Paper!