An open-access review of the entirety of the UW Activa PC+S effort to develop adaptive neuromodulation algorithms to improve the treatment of Essential Tremor has been published in Frontiers in Neuroscience. The full paper is viewable here: https://doi.org/10.3389/fnins.2021.749705
Congratulations to all of the students who have worked on this project over the last seven years!
At the upcoming EMBC 2021 we’re excited to present our latest research results from the fields of BCI and DBS. Congratulations to all students involved for getting their hard work published! Stay tuned for final paper links but this year we’ll be presenting two papers:
“Robustness of Beta Desynchronization from Chronically Implanted Cortical Electrodes on Multiple Time Scales” by Tomek Fraczek, Andrew Ko, Howard Chizeck, and Jeffrey Herron. Available here: https://ieeexplore.ieee.org/abstract/document/9629927
“A Platform for Virtual Reality Task Design with Intracranial Electrodes” by Co-first authors Maurice Montag and Courtnie Paschall, along with Jeff Ojemann, Rajesh Rao, and Jeffrey Herron. Available here: https://ieeexplore.ieee.org/abstract/document/9630231
Three papers are being presented at NER 2021 next week detailing ongoing work in the evaluating the sensing capabilities of directional DBS electrodes, stimulation ramp rate testing to support closed-loop DBS studies, and new architectures to support future research tool software development. Congratulations to all the students and collaborators who got their papers accepted to NER 2021!
C. Paschall, L. Levinson, J. Ojemann, A. Ko, J. Herron “Data-Driven Spectral Features of Directional DBS Electrodes and dDBS-ECoG Connectivity”
M. Petrucci, K. Wilkins, G. Orthlieb, Y. Kehnemouyi, J. O’Day, J. Herron, H. Bronte-Stewart “Ramp Rate Evaluation and Configuration for Safe and Tolerable Closed-Loop Deep Brain Stimulation”
B. Roarr, R. Perrone, F. Jamshed, R. Gilron, T. Denison, P. Starr, J. Herron, D. Borton “OMNI: Open Mind Neuromodulation Interface for Accelerated Research and Discovery“
A collaboration between the UW adaptive DBS team and researchers at the University of Freiburg have resulted in an open access publication detailing a the results of a new data-driven algorithm approach to the treatment of Essential Tremor using adaptive DBS methods.
Master’s student Kazi (Sabrina) Sonnet will be presenting her work on classifying essential tremor symptom classification using drawing task data at the IEEE BIBE2020 Conference on Monday, October 26th!
PhD student Ben Ferleger’s work in demonstrating closed-loop DBS methods for treating essential tremor using a fully implanted system has been published in the Journal of Neural Engineering. Check out the full article here, and the prepublication version here.
An ongoing collaboration with Tim Denison of Oxford University has resulted in a publication posted to bioRxiv, check it out here.
Five papers are going to be presented at EMBC covering ongoing work associated with closed-loop deep brain stimuilation (DBS) for Parkinson’s Disease and Essential Tremor, automated movement disorder symptom assessment techniques using mobile applications, and sleep stage classification based on invasive electrocorticography signals in epilepsy patients. Congratulations to all the students at University of Washington and our collaborators at Stanford who wrote these papers that were accepted to EMBC!
S. Cooper, B. Ferleger, A. Ko, J. Herron, H. Chizeck, “Rebound effect in deep brain stimulation for essential tremor and symptom severity estimation from neural data”
B. Ferleger, K. Sonnet, T. Morriss, A. Ko, H. Chizeck, J. Herron, “A tablet- and mobile-based application for remote diagnosis and analysis of movement disorder symptoms”
S. Sun, L. Jiang, S. Peterson, J. Herron, K. Weaver, A. Ko, J. Ojemann, R. Rao, “Unsupervised Sleep and Wake State Identification in Long-Term Neural Recordings”
J. O’Day, Y. Kehnemouyi, M. Petrucci, R. Anderson, J. Herron, H. Bronte-Stewart, “Demonstration of Kinematic-Based Closed-Loop Deep Brain Stimulation for Mitigating Freezing of Gait in People with Parkinson’s Disease”
M. Petrucci, R. Anderson, J. O’Day, Y. Kehnemouyi, J. Herron, H. Bronte-Stewart, “A Closed-Loop Deep Brain Stimulation Approach for Mitigating Burst Durations in People with Parkinson’s Disease”
Today, PhD student Ben Ferleger had his work on closed-loop DBS for essential tremor using a fully embedded algorithm posted to medRxiv. Check out the full paper here
A poster detailing work done in collaboration with Dr. Greg Worrell and Dr. Ben Brinkmann at the Mayo Clinic will be presented at the upcoming American Epilepsy Society meeting. The poster, titled “Epilepsy Personal Assistant Device – A Mobile Platform for Brain State, Dense Behavioral and Physiology Tracking, and Controlling Adaptive Stimulation” details work on a chronic monitoring system leveraging the Medtronic Summit System. See the full abstract here.