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Clurman, Bruce, PhD

Professor, Medical Oncology
Adjunct Professor, Laboratory Medicine & Pathology, Oral Health Sciences
Primary Institution: FHCRC
Program: M3D PhD Program
Mentor: M3D Research Mentor
Email: bclurman@fredhutch.org
Office Location: Fred Hutchinson Cancer Research Center - D2-114

Faculty Profile Website

Lab Website

Research & Clinical Summary

The pathways that regulate cell growth and division.

Interests: Cancer

Publications

The following publications were retrieved from PubMed:

Welcker M, Clurman BE,
“Oncoprotein ubiquitylation: dimers, degrons, and degradation.”
Cell cycle (Georgetown, Tex.) 13.12 (2014): 1829-30.

Davis RJ, Welcker M, Clurman BE,
“Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.”
Cancer cell 26.4 (2014 Oct 13): 455-64.

Zhao H, Faltermeier CM, Mendelsohn L, Porter PL, Clurman BE, Roberts JM,
“Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy.”
Oncotarget 5.24 (2014 Dec 30): 12704-14.

Park E, Lee B, Clurman BE, Lee K,
“NUP50 is necessary for the survival of primordial germ cells in mouse embryos.”
Reproduction (Cambridge, England) 151.1 (2016 Jan): 51-8.

Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, Baliga NS, Moffat J, Lin Q, Li XN, Nam DH, Lee J, Pollard SM, Zhu J, Delrow JJ, Clurman BE, Olson JM, Paddison PJ,
“Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.”
Cell reports 13.11 (2015 Dec 22): 2425-2439.