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Maerz, Megan

Program: M3D PhD Program
Entry Year: Autumn 2019
Previous Institution/Degree: UC Davis
Department: Laboratory Medicine and Pathology
Lab PI: Chetan Seshadri, MD
Box Number: 357470
Email: mdmaerz@uw.edu

Research Focus

The role of γδ T cells in the immune response against Mycobacterium tuberculosis

Awards

NIH T32 Training Grant, 2020-2021

People’s Choice Award, UW Three Minute Thesis (3MT), March 2023 

Early Career Scientist Award, Seattle TB Research Advancement Center (SEATRAC), April 2023

Publications

Chriswell, M. E., Lefferts, A. R., Clay, M. R., Hsu, A. R., Seifert, J., Feser, M. L., Rims, C., Bloom, M. S., Bemis, E. A., Liu, S., Maerz, M. D., Frank, D. N., Demoruelle, M. K., Deane, K. D., James, E. A., Buckner, J. H., Robinson, W. H., Holers, V. M., & Kuhn, K. A. (2022). Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. Science translational medicine, 14(668), eabn5166.

Speake, C., Habib, T., Lambert, K., Hundhausen, C., Lord, S., Dufort, M. J., Skinner, S. O., Hu, A., Kinsman, M., Jones, B. E., Maerz, M. D., Tatum, M., Hocking, A. M., Nepom, G. T., Greenbaum, C. J., & Buckner, J. H. (2022). IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function. JCI insight, 7(22), e159436.

Lambert, K., Diggins, K. E., Jones, B. E., Hundhausen, C., Maerz, M. D., Hocking, A. M., Sanda, S., Greenbaum, C. J., Linsley, P. S., Cerosaletti, K., & Buckner, J. H. (2022). IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation. Frontiers in immunology, 13, 935394.

Jones, B. E., Maerz, M. D., Bahnson, H. T., Somasundaram, A., McCarthy, L. H., Speake, C., & Buckner, J. H. (2022). Fewer LAG-3+ T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes. Journal of immunology (Baltimore, Md. : 1950), 208(3), 594–602.

Jones, B. E., Maerz, M. D., & Buckner, J. H. (2018). IL-6: a cytokine at the crossroads of autoimmunity. Current opinion in immunology, 55, 9–14.

 

First-Year Rotations (2019-2020)

Autumn: Aude Chapuis, MD

Winter: Chetan Seshadri, MD 

Spring: Paul Nghiem, MD, PhD