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Wang, Shiyi

Program: M3D PhD Program
Entry Year: Autumn 2020
Previous Institution/Degree: Scripps Research Institute
Department: Laboratory Medicine and Pathology
Lab PI: Bruce Torbett, PhD
Box Number: 357470
Email: syiwang@uw.edu

Research Focus

Virology, sequencing, and bioinformatics

Publications

1. Wang S, Sotcheff SL, Gallardo CM, Jaworski E, Torbett BE, Routh AL. Covariation of viral recombination with single nucleotide variants during virus evolution revealed by CoVaMa. Nucleic Acids Res. 2022 Apr 22;50(7):e41. doi: 10.1093/nar/gkab1259. PMID: 35018461; PMCID: PMC9023271.

2. Gallardo CM, Wang S, Montiel-Garcia DJ, Little SJ, Smith DM, Routh AL, Torbett BE. MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution. Nucleic Acids Res. 2021 Jul 9;49(12):e70. doi: 10.1093/nar/gkab231. PMID: 33849057; PMCID: PMC8266615.

3. Zhang X, Chen W, Gao Q, Yang J, Yan X, Zhao H, Su L, Yang M, Gao C, Yao Y, Inoki K, Li D, Shao R, Wang S, Sahoo N, Kudo F, Eguchi T, Ruan B, Xu H. Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR. PLoS Biol. 2019 May 21;17(5):e3000252. doi: 10.1371/journal.pbio.3000252. PMID: 31112550; PMCID: PMC6528971.

4. Liu R, Xu C, Zhang Q, Wang S, Fang W. Evolution of the chitin synthase gene family correlates with fungal morphogenesis and adaption to ecological niches. Sci Rep. 2017 Mar 16;7:44527. doi: 10.1038/srep44527. PMID: 28300148; PMCID: PMC5353729.