**UPDATE 11/1/2024 *** This position has been filled.

We have an immediate opening for a motivated and energetic scientist interested in translational neuroscience research and drug discovery.

This is a highly interdisciplinary and collaborative project at the interface of preclinical epilepsy and Alzheimer’s disease research, with a focus on the behavioral and pathophysiological elucidation of the mechanisms of hyperexcitability in the aging and degenerating brain. This research project pairs transgenic models with a diversity of behavioral techniques and provides the opportunity to interact with scientists and clinicians from different fields of neuroscience and neurology. The project also provides the opportunity to apply novel molecular neuroscience techniques to the study of behavioral neuroscience. The successful applicant will also learn to manage laboratory personnel including research scientists and students, contribute to grant writing, and be primary author on manuscripts. Teaching opportunities may be available to qualified and interested candidates.

Main research responsibilities include:

• Chronic video-EEG monitoring and small animal surgery.
• Pharmacological studies to assess disease modification and prevention in rodent models of neurological disease.
• Apply advanced animal behavioral techniques to the study of comorbidities of epilepsy and Alzheimer’s disease.
• Perform in vivopharmacokinetic/pharmacodynamic studies in relevant preclinical models of aging-related epilepsy and Alzheimer’s disease.
• Deploy established methods to assess pathophysiological changes associated with neurological insult in relevant aging-related models of epilepsy and Alzheimer’s disease, which may include fluorescence microscopy, ELISA, electrophoresis, and advanced mRNA/miRNA expression profiling techniques.

Interested applicants should contact Dr. Barker-Haliski directly (mhaliski at UW dot edu)