Dr. Michele Basso presented recent research results from her team in the broader context of perceptual decision making, based on the following paper: https://www.nature.com/articles/s41593-021-00878-6.
Abstract: Trained monkeys performed a two-choice perceptual decision-making task in which they reported the perceived orientation of a dynamic Glass pattern, before and after unilateral, reversible, inactivation of a brainstem area – the superior colliculus (SC) – involved in preparing eye movements. We found that unilateral SC inactivation produced significant decision biases and changes in reaction times consistent with a causal role for the primate SC in perceptual decision-making. Fitting signal detection theory and sequential sampling models to the data showed that SC inactivation produced a decrease in the relative evidence for contralateral decisions, as if adding a constant offset to a time-varying evidence signal for the ipsilateral choice. The results provide causal evidence for an embodied cognition model of perceptual decision-making and provide compelling evidence that the SC of primates (a brainstem structure) plays a causal role in how evidence is computed for decisions – a process usually attributed to the forebrain.
About the Speaker:
Dr. Michele Basso is Professor of Biological Structure and Director of the Washington National Primate Research Center at the University of Washington, Seattle.