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Young Kwon
Assistant Professor of Biochemistry
B.A. 1997, Yonsei University
M.S. 1999, Yonsei University
Ph.D. 2008, Johns Hopkins University
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Honors
- 2007 The Paul Ehrlich Research Award, The Johns Hopkins University School of Medicine
- 2009 Tom Elkins Memorial Lecture, Neurobiology of Drosophila meeting at Cold Spring Harbor
- 2009-2011 Damon Runyon Cancer Research Fellowship
Research
Our laboratory studies the mechanisms that control growth and wasting, two opposite processes involved in animal development, homeostasis and aging. Currently, we focus on elucidating comprehensive signaling networks that control organ growth and wasting using proteomics and functional genomics. Additionally, we aim to understand the genetic basis of organ growth and wasting using fruit flies. To this end, we established a fly model of systemic organ wasting, which was highlighted in the following articles: Nature, Science Signaling, The Scientist and Eurekalert!
- A waste of insulin interference. Nature (2015)
- Wasting away without insulin. Science Signaling (2015)
- Insulin Interference Triggers Cancer-linked Cachexia. The Scientist (2015)
- Origin of Cancer Wasting Identified in Fruit Flies. Eurekalert! (2015)
Publications:
Showing most recent results from Scopus…
- Kwon Y. et al. Systemic organ wasting induced by localized expression of the secreted Insulin/IGF antagonist ImpL2 Developmental Cell 2015-01-01; 33(1):36-47. [Search PubMed] [View in Scopus]
- Kwon Y. et al. The Hippo signaling pathway interactome Science 2013-01-01; 342(6159):737-740. [Search PubMed] [View in Scopus]
- Sun X. et al. An advanced method for identifying protein-protein interaction by analyzing TAP/MS data Proceedings – 2012 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2012 2012-12-01; :250-255. [Search PubMed] [View in Scopus]
- Neumüller R. et al. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes Genetics 2012-03-01; 190(3):931-940. [Search PubMed] [View in Scopus]
- Booker M. et al. False negative rates in Drosophila cell-based RNAi screens: A case study BMC Genomics 2011-01-20; 12. [Search PubMed] [View in Scopus]
