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14th International Conference of the Metabolomics Society
The 14th International Conference of the Metabolomics Society will be held at the Washington State Convention Center in downtown Seattle, June 24 – 28, 2018. Dan Raftery is the chair of the scientific organizing committee. The conference has an overall goal of Making...
Emerging metabolomics research in the model organism, Caenorhabditis elegans
An overview by Chun-Ling Sun, PhD, Acting Instructor. Recent publications have attracted profound interests in metabolome and metabolism research in the powerful genetic model, Caenorhabditis elegans. Moreover, in a recent worm conference, the organization committee...
A class of reactive acyl-CoA species reveals the non-enzymatic origins of protein acylation
Wagner et al. Cell Metabolism, April 2017. Mitochondria and Metabolism Journal Club (June 2017). Presented by: Arianne Caudal, graduate PhD student in the Tian Lab. Succinyl-CoA is an efficient acylating agent Post-translational modifications to protein side chains...
Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis.
By Pouli et al. Science Translational Medicine, November 2016 Mitochondria and Metabolism Journal Club – Presented by Michelle Giarmarco, Doctoral Candidate from the Hurley Lab – January 2017 A new tool for imaging NADH and mitochondria in vivo In this study,...
Lactate metabolism is associated with mammalian mitochondria
Presented by Connor Jankowski Lactate metabolism is associated with mammalian mitochondria. Chen et al., Nature Chemical Biology, Sep. 2016 An Intracellular Fate for Lactate In this study, Chen. et al show that fermenting HeLa and H460 cells are able to use exogenous...
Nutritional ketosis alters fuel preference and thereby endurance performance in athletes.
Mitochondria and Metabolism Journal Club – Presented by Lauren Abell – October 2016 Nutritional ketosis alters fuel preference and thereby endurance performance in athletes. By Cox et al. Cell Metabolism, Aug 2016 Ketone Supplementation: Does it promote physical...
Biochemistry of Exercise-induced Metabolic Acidosis
Mitochondria and Metabolism Journal Club - September 2016 Journal article presented by Michal Handzlik, PhD, Senior Fellow in Tian Laboratory It is well recognized that both skeletal and cardiac muscle consume more carbohydrates during increased workload (e.g. high...
Targeting Mitochondria to Restore Failed Adaptation to Exercise in Diabetes
Mitochondria and Metabolism Journal Club Presented by Yushekia S. Woodford, MS2- June 2016 Targeting Mitochondria to Restore Failed Adaptation to Exercise in Diabetes – by Geary et al., Biochemical Society 2014 Introduction: The translational research group focuses on...
Advances in Metabolomics
Daniel Raftery, PhD, Director of the Metabolomics Core Facility. The rapidly growing field of metabolomics focuses on the quantitative analysis of many hundreds of metabolites in complex specimens that include bio-fluids, tissues and cells. Small molecule metabolites...