Shabnam Salimi, MD, PhD

  • Department of Anesthesiology and Pain Medicine

  • Acting Instructor

Research Interests

 

Education

  • Kermanshah Univerity of Medical Sciences, MD, 2003
  • Umea Univerity, MSc, 2008
  • University of Maryland Baltimore, Postdoctoral Study, Genetic Epidemiology, 2015
  • Fellowship American Heart Association
  • University of Maryland Baltimore, Postdoct oral Study,Epidemiology of Aging, 2017

 

Selected Publications

  1. Salimi S, Nawi N, Seliger S, Parsa A. Periodontal disease, renal dysfunction and heightened leukocytosis. Analysis of NHANES data. Nephron Clin Pract 2014; 28(1-2):107-14.
  2. Murigi FN, Mohindra P, Hung C, Salimi S, Goetz W, Pavlovic R, Jackson IL, Vujaskovic Z. Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice. Radiat Res 2015; 184:422-32.
  3. Seliger SL, Salimi S, Pierre V, Giffuni J, Katzel L, Parsa A. Microvascular endothelial dysfunction is associated with albuminuria and CKD. BMC 2016; 13:17-82.
  4. Salimi S, Lewis JP, Yerges-Armstrong LM, Mitchell BD, Saeed F, O’Connell JR, Perry JA, Ryan KA, Shuldiner AR, Parsa A. Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons with Heightened Platelet Aggregation. J Am Heart Assoc 2016; 31:5.
  5. Parsa A, Kanetsky PA, Xiao R, Gupta J, Mitra N, Limou S, Xie D, Xu H, Anderson AH, Ojo A, Kusek JW, Lora CM, Hamm LL, He J, Sandholm N, Jeff J, Raj DE, Böger CA,
  6. Bottinger E, Salimi S, Parekh RS, Adler SG, Langefeld CD, Bowden DW; FIND Consortium., Groop PH, Forsblom C, Freedman BI, Lipkowitz M, Fox CS, Winkler CA,
  7. Feldman HI; and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study. J Am Soc Nephrol 2017; 28:923-934.
  8. Salimi S, Guralnik J, Shardell M, Huang Y, Orwig D, Gruber-Baldini A, Magaziner J. Trajectories of inflammation and frailty following hip fracture: Baltimore Hip Fracture Study. J Am Geriatr Soc 2018;66:804-811.
  9. Choi CS, Lim W, Salimi S, YEJ, Lee-Kwon W, Lee HH, Lee JH, Mitchell BD, Sanada S,Parsa A, Kwon MH. TonEBP mediates hyperglycemia-induced inflammation, vascular and renal injury. J Am Soc Nephrol. 2018;29:492-504.
  10. Salimi S, Shardell M, Miller R, Gruber-Baldini AL, Orwig D, Fedarko N, Hochberg MC, Guralnik JM, Magaziner J. Soluble Tumor Necrosis Factor Alpha Receptor 1, Bone Resorption, and Bone Mineral Density in the Year Following Hip Fractures: The Baltimore Hip Studies. J Bone Miner Res. 2018 Sep;33(9):1649-1656.
  11. Wang X, Salimi S, Deng Z, Perry J, Ryan KA, Li Z, Liu D, Streeten E, Shuldiner AR, Fu M. Evaluation of WISP1 as a candidate gene for bone mineral density in the Old Order Amish. Sci Rep. 2018;8:7141.
  12. Polfus LM, Raffield LM, Wheeler MM, Tracy RP, Lange LA, Lettre G, Miller A, Correa A, BowlerRP, Bis JC, Salimi S, Jenny NS, Pankratz N, Wang B, Preuss MH, Zhou Moscati A, Nadkarni GN, Loos RJF, Zhong X, Li B, Johnsen JM, Nickerson DA, Reiner AP, Auer PL; NHLBI Trans-Omics for Precision Medicine Consortium. Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans. Hum Mol Genet. 2019;28:515-523.
  13. NHLBI TOPMed Lipid working Group. Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nat Commun. 2018;9:3391.
  14. NHLBI TOPMed Lipids Working Group. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018;9:2606.
  15. Snyder JM, Snider TA, Ciol MA, Wilkinson JE, Imai DM, Casey KM, Vilches-Moure JG, Pettan-Brewer C, Pillai SPS, Carrasco SE, Salimi S, Ladiges W. Validation of a geropathology grading system for aging mouse studies. Geroscience 2019; 41(4):455-465.
  16. Ferrucci L, Gonzalez-Freier M, Fabbri E, Simonsick E, Tanaka T, Moore Z, Salimi S, Sierra F, de Cabo R. Measuring biological aging in humans: A quest. Aging Cell 2020; 19(2):e13080
  17. Raffield LM, Iyengar AK, Wang B, Gaynor SM, Spracklen CN, Zhong X, Kowalski MH, Salimi S, et al. Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts. Am J Hum Genet 2020; 2;106.
  18. Salimi S, Yanosky JD, Huang D, Montressor-Lopez J, Vogel R, Reed RM, Mitchell BD, Puett RC. Long-term Exposure to Particulate Air Pollution and Brachial Artery Flow-Mediated Dilation in the Old Order Amish. Environ Heath 2020;14; 19:50.
  19. Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium. De Novo Mutations Across 1,465 Diverse Genomes Reveal Mutational Insights and Reductions in the Amish Founder Population. Proc Natl Acad Sci USA, 2020, 4;117(5):2560-2569.
  20. Kachroo P, Hecker J, Chawes BL, Ahluwalia TS, et al. National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma. Chest 2019; 156:1068-1079.
    NHLBI TOPMed NeuroCognitive Working Group. Whole-genome sequence analyses of brain imaging measures in the Framingham Study. Neurology 2018;16;90:e188-e196
  21. Salimi S, Hamlyn JM. COVID-19 and Crosstalk With the Hallmarks of Aging. J Gerontol A Biol Sci Med Sci; 2020 Jun 16;glaa149.
  22. Salimi S, Vehtari A, Salive Body Clock: Matching Personalized Multimorbidity and Fast Aging Using Information Entropy

Laboratory:  Raftery Lab

Contact Information

Mitochondria and Metabolism Center
850 Republican Street, Room N111
University of Washington, Box 358057
Seattle, WA 98109-8057
Phone: 206-221-0348
Fax: 206-616-4819
Email: Mike Crowder