• Researcher, Mitochondria and Metabolism Center

• Assistant Professor, Anesthesiology and Pain Medicine
  

• Laboratory: Van Gilst

Currently accepting rotating graduate students, for more information, contact Dr. Van Gilst at vangilst@uw.edu

Research Interests

• Nuclear receptors and nutritional response

• Impact of nutrition on aging and reproduction

• Nutritional and developmental control of lipid metabolism

Honors and Awards

• Helen Hay Whitney Foundation Postdoctoral Fellowship: 1998-2001

• American Diabetes Association Junior Faculty Award: 2007-2009

• Glenn Award for Outstanding Research in the Biology of Aging: 2010

Selected Publications 

Kaufman DM, Wu X, Scott BA, Itani OA, Van Gilst MR, Bruce JE, Crowder CM (2017) Ageing and hypoxia cause protein aggregation in mitochondria. Cell Death Differ. Oct 24(10), 1730-1738

Burnaevskiy N, Chen S, Mailig M, Reynolds A, Karanth S, Mendenhall A, Van Gilst MR, Kaeberlein M (2018) Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in elegans. Elife Aug 2;7, pii: e36194

Itani OA, Zhong X, Tang, X, Scott BA, Yan JY, Flibotte S, Hsieh AC, Bruce, JE, Van Gilst MR, Crowder CMC. (2021) Coordinate regulation of ribosome and tRNA biogenesis controls hypoxic injury and translation.  Current Biology, Jan 11, 128-137  e33157031

Van Gilst MR, Hadjivassiliou H, Jolly A and Yamamoto KR (2005) Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans. PLoS Biology 3, 301-312.

Van Gilst MR, Hadjivassiliou H and Yamamoto KR (2005) A C. elegans nutrient response system partially dependent upon NHR-49. Proceedings of the National Academy of Sciences 102, 13496-13501.

Perez CL and Van Gilst MR (2008) A ¹³C isotope labeling strategy reveals the impact of insulin signaling on lipogenesis in C. elegans. Cell Metabolism 8, 266-274.

Hahn-Windgassen A and Van Gilst MR (2009) The Caenorhabditis elegans HNF4α homolog, NHR-31, mediates excretory tube growth and function through coordinate regulation of the vacuolar ATPase. PLoS Genetics 5, e1000553.

Angelo G and Van Gilst MR (2009) Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science 326, 954-958.

Pathare PP, Lin A, Bornfeldt KE, Taubert S and Van Gilst MR (2012) Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships. PLoS Genetics 8(4):e1002645.